Medical Papers

Medical journals are published regularly to communicate new research to clinicians, medical scientists, and other healthcare workers

Breast-Cancer Tumor Size, Overdiagnosis, and Mammography Screening Effectiveness

Atopic dermatitis is a chronic, relapsing inflammatory skin disease that is characterized by the up-regulation of type 2 immune responses (including those involving type 2 helper T cells),1,2 an impai

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10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer

The management of clinically localized prostate cancer that is detected on the basis of prostate-specific antigen (PSA) levels remains controversial. In the United States alone, an estimated 180,890 c

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Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant Therapy

Ipilimumab, a fully human monoclonal antibody that blocks cytotoxic T-lymphocyte antigen 4 (CTLA-4) to augment antitumor immune responses, was approved by the Food and Drug Administration (FDA) and th

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Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis

Atopic dermatitis is a chronic, relapsing inflammatory skin disease that is characterized by the up-regulation of type 2 immune responses (including those involving type 2 helper T cells),1,2 an impai

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A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection

The 2014–2016 Ebola outbreak in West Africa was unprecedented in sheer scope, duration, and number of human casualties.1,2 The outbreak resulted in more than 28,000 suspected or confirmed cases

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Adjuvant Sunitinib in High-Risk Renal-Cell Carcinoma after Nephrectomy

Each year, approximately 300,000 persons worldwide are diagnosed with renal-cell carcinoma, resulting in 129,000 deaths.1,2 The prognosis for patients with renal-cell carcinoma is dependent on the sta

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Mapping Plasmodium falciparum Mortality in Africa between 1990 and 2015

Measuring the burden of malaria according to age and geographic area and over time is important for malaria-control programs and health care providers for planning, implementing, monitoring, and evalu

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Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer

Approximately 23 to 28% of patients with advanced non–small-cell lung cancer (NSCLC) have a high level of programmed death ligand 1 (PD-L1) expression, which is defined as membranous PD-L1 expre

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Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck

Squamous-cell carcinoma of the head and neck is a major cause of cancer-associated illness and death, with more than 600,000 cases diagnosed annually worldwide.1 Most patients present with locoregiona

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Niraparib Maintenance Therapy in Platinum-Sensitive, Recurrent Ovarian Cancer

Ovarian cancer is a leading cause of death from gynecologic cancers worldwide.1,2 Despite a high initial response rate to platinum and taxane treatment in patients with advanced cancer, the effectiven

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Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer

Up to 75% of breast cancers express the estrogen receptor or progesterone receptor (hormone-receptor [HR]–positive).1,2 Endocrine therapy is the standard of care for postmenopausal women with ad

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Guillain–Barré Syndrome Associated with Zika Virus Infection in Colombia

Zika virus (ZIKV), a mosquito-borne RNA flavivirus, has caused a major outbreak in the Americas that began in 2014.1 ZIKV infection manifests as a self-limited febrile syndrome associated with rash, c

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Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection1 and is a leading cause of death worldwide. Septic shock is the most severe form of the cond

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A Measles Outbreak in an Underimmunized Amish Community in Ohio

Measles is a highly contagious, albeit vaccine-preventable, disease that can lead to serious complications. Although endemic transmission of measles in the United States was declared to be eliminated

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How to overcome fitness obstacles

If you’re like me, the quest to be in shape and manage weight feels overwhelming. And, as if the quest to be fit isn’t hard enough, there’s often other obstacles to overcome: health

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Carrying on with a Healthy Life

outline:we're so bustling speeding for the duration of our time to day revel in that we do not set apart the opportunity to attend to ourselves. it's truely no huge marvel that so massive qu

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Glow your skin with " Antioxidants "

IntroductionThe advantages of antioxidant rich diet – for inside and out healthy body – can't be overemphasized. that's true even once it includes getting a more beneficial compo

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Overview of Hypertention

Causes :Essential ( primary ) : related to age , sex, genetics, race, DM  lack of exercise and smoking.secondary : which result from underlying causes such as :Drugs : steroids, contraceptive pil

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Stable and Unstable Angina

Stable anginaAngina pectoris, commonly known as angina, is the sensation of chest pain , pressure, or squeezing, often due to not enough blood flow to the heart muscle as a result of obstruction 

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Diabetes Mellitus

Introduction :Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period. Symptoms of high blood suga

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Leukemia

What is leukemia :Is a group of cancers that usually begin in the bone marrow and result in high numbers of abnormal white blood cells.These white blood cells are not fully developed and are called bl

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Pneumonia

What is Pneumonia :  Is an inflammatory condition of the lung affecting primarily the microscopic air sacs known as alveoli. Typical signs and symptoms include a var

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Tetralogy of Falot

It's the most common type of cyanotic heart disease.Features of the disease :1. Pulmonary stenosis2. Right ventricular hypertrophy3. Ventricular septal defect4. Overriding of aortaCauses of the d

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Overview about LASIK surgery

LASIK, an acronym for Laser-assisted In Situ Keratomileusis, is a form of refractive laser eye surgery procedure performed by ophthalmologists intended for correcting vision. The procedure is usually

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Simple Tips To Get More Active

You know you should be getting some sort of exercise, you know of all the health benefits that come with a more active lifestyle. You’ve tried the whole Gym thing, but it just wasn’t for y

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Micheala Aldred, Ph.D.

Micheala Aldred, PhD, is an Associate Staff Researcher in the Cleveland Clinic Genomic Medicine Inst